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It can cause a temporary surge in certain hormones, such as luteinizing hormone (LH), which stimulates testosterone production in the testes

BMJ article on candy cigarettes Top photo by Sally Mann - Candy Cigarette - 1989 - reproduced under fair use doctrine

instead, it evolves gradually, often without noticeable pain, which makes it especially dangerous

doi: 10.1111/j.1360-0443.1994.tb00890.x

That gets us back to Mark Twain: he could stop using cigarettes for a while, but ultimately his brain led him right back to nicotine, creating an endless loop in which he "gave up" smoking thousands of times, only to find himself smoking again a few days later

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