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Inconsistencies in confounder adjustment across studies could bias the pooled estimates, limiting the causal interpretation of the findings

For this study, the researchers used data on 21,618 healthy adult participants from the first four waves (20132018) of the nationally representative Population Assessment of Tobacco and Health (PATH), which is the most comprehensive national survey of tobacco and e-cigarette use to date

The observation that this review found that most studies on vaping and cessation (all but four out of 91) failed to constitute reliable scientific evidence is important, because public health researchers who oppose vaping sometimes claim that the weight of the evidence shows that ecigarette use does not aid cessation

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