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Lung diseases: Smoking is a major cause of chronic obstructive pulmonary disease (COPD), which includes chronic bronchitis and emphysema

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Although not all responded to cigarette smoke in the same way some, including those known to cause invasive infections, showed increased resistance to the antibiotic rifampicin and increased invasiveness and persistence

Without publicly led interventions on the rising burden of non-communicable diseases, we risk health systems collapse.

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"If I knew this was going to happen, I'd have sold it." Ayoub said he's been in the tobacco business 18 years but never has seen price increases hit this hard