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An early clinical trial (ClinicalTrials.gov identifier NCT03865121) also proposed nasal administration as the optimal nicotinic therapy in PD patients

She stands, stiffly, as three men leer and cackle

Ethics declarations Ethics approval and consent to participate Not applicable Consent for publication Not applicable Competing interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

and more importantly, it served as a reminder of why I detest smoking with a passion

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As of July 2018, Insilico and CCARL are independent companies engaged in aging and disease research, new affiliations are A.Z., P.M., E.L., K.K., A.A