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Makers of the "vaping" devices launched a flood of new products in the United States ahead of new federal regulations, taking effect on Monday, that require companies to submit e-cigarettes for government approval before marketing them, according to company officials and industry experts

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In parallel, with the development of new technologies, human relevant in vitro models for toxicity assessment have been proposed such as three dimensional (3D) advanced models or reconstructed human airway tissues [17, 18]

DNA adduct burden and tobacco carcinogenesis