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You can vary your injection day by 1 day without reducing efficacy, since semaglutide's 7-day half-life creates a forgiving window

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Gao Q, et al

In experimental systems, DSIP has been shown to influence second messenger activity and hormonal signaling cascades linked to the hypothalamicpituitaryadrenal axis, including regulation of adrenocorticotropic hormone and related endocrine mediators [4]