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doi: 10.3390/coatings11050501 139 WangKYangXWuZWangHLiQMeiHet al

Together, these effects influence major CVD biomarkers, including reductions in: LDL-cholesterol hs-CRP TMAO SBP/DBP Oxidized LDL IL-6/TNF- Thus, the black garlicprobiotic synbiotic approach exerts pleiotropic, multi-axis benefits, simultaneously targeting microbial, metabolic, immune, and vascular functions, with significant potential for integration into functional cardioprotective nutrition

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Adverse Reactions/Side Effects The following serious adverse reactions are described below or elsewhere in the prescribing information: Risk of Thyroid C-Cell Tumors [see Warnings and Precautions (5.1)] Acute Pancreatitis [see Warnings and Precautions (5.2)] Acute Gallbladder Disease [see Warnings and Precautions (5.3)] Risk for Hypoglycemia with Concomitant Use of Anti-Diabetic Therapy [see Warnings and Precautions (5.4)] Heart Rate Increase [see Warnings and Precautions (5.5)] Acute Kidney Injury Due to Volume Depletion [see Warnings and Precautions (5.6)] Severe Gastrointestinal Adverse Reactions [see Warnings and Precautions (5.7)] Hypersensitivity Reactions [see Warnings and Precautions (5.8)] Pulmonary Aspiration During General Anesthesia or Deep Sedation [see Warnings and Precautions (5.9)] 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice

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