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Curr Med Chem (2013) 20:132331

Therapeutic Implications: Restoring the Glutathione-Mitochondrial-Vascular Axis Understanding glutathione as a central integrator of redox, mitochondrial, and vascular signaling provides a clear rationale for interventions designed to restore homeostasis and cardiometabolic resilience

However, ABHD11 inhibition had mixed effects on KDM activity, and only histone 3 lysine 4 trimethylation (H3K4me3) was increased, indicating that the effect of ABHD11 inhibition on 2-OGDDs is not uniform across this enzyme group (Extended Data Fig

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