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To explore how well GLP-1R agonists access various parts of the brain, Sechers team labeled various agonists with fluorescent tags so that when they administered the agonists to mice, they could see which areas of their brains lit up
Wharton, the STEP 5 Study Group, Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial
Florida Bariatric and Plastic Surgery MD does not claim to be affiliated with or endorsed by Eli Lilly (Mounjaro/Zepbound) or Novo Nordisk (Ozempic/Wegovy)
Study found that increasing endogenous and exogenous intestinal SCFAs can stimulate intestinal endocrine cells to secrete GLP-1 and PYY by binding to GPR41 and GPR43 (Tian et al., 2024)
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10.3389/fbioe.2023.1104126
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