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At the day of vaccination, mice were anesthetized intraperitoneally with ZRF cocktail

A continued, unresolved imbalance between effector and regulatory immune responses further exacerbates inflammation that ultimately causes tissue and organ damage

It is characterized by extracellular plaque formation comprising of amyloid beta (A) and intracellular neurofibrillary tangles (NFT) consisting of hyper phosphorylated tau proteins, that collectively leads to neuroinflammation and ultimately neuronal death (Kumar et al., 2022

Any samples that have not been treated with 2-vinylpyridine will yield Total GSH levels