semaglutide chemical synthesis | C187H291N45O59 | CID 56843331 Semaglutide | 910463-68-2

SURMOUNT-MAINTAIN (Horn 2026, 112 weeks): continued top dose -21.9% vs 5 mg step-down -16.6% vs placebo -9.9%, rescue therapy 8/25/67%: Aronne JAMA 2024

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While chest pain is not a common side effect, it has been reported

Managing Side Effects and Workout Performance Nausea is the most commonly reported side effect of semaglutide, affecting roughly 2030% of users in clinical trials

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