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In add-on therapy, starting with an SGLT2 inhibitor may be preferable, especially for patients with established diabetic kidney disease, owing to its well-documented benefits in reducing intraglomerular pressure and albuminuria

178 Guideline Statement 19 If Hunner lesions are present, then fulguration (with electrocautery) and/or injection of triamcinolone should be performed

When data were not normally distributed the non-parametric tests such as the Mann-Whitney U-test or KruskalWallis analysis of variance were used

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Ghrelin, an intestinal hormone crucial for nigrostriatal dopamine homeostasis, shows impaired secretion in PD patients [158, 159]