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GLP-1 therapies like Wegovy and Ozempic have helped patients lose significant weight, sometimes as much as 15-20% of their body weight

showed 2-10 fold GH increases and 1.5-3 fold IGF-1 elevation in healthy adults receiving CJC-1295 DAC with IGF-1 remaining above baseline for up to 28 days after multiple doses (PMID: 16352683)