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Glucose tolerance tests Mice were submitted to habituations 12 weeks before starting metabolic tests

Combined with sensitivity analyses, we infer that the imprecision leading to downgraded evidence quality for certain outcomes may be linked to differences in study follow-up duration: short-term follow-up studies might suffer from increased random error or insufficient statistical power due to inadequate accumulation of cardiovascular events

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These models closely mimic the architecture and functionality of human tissues, providing a more accurate platform for studying TGF- signaling in obesity-related diseases

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