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However, the specific relationship between the OBS and gallstone risk remains poorly understood

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PMID: 106 ShuWBaumannBHSongYLiuYWuXDunaiefJL

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FDA is requesting that the risk be removed from the warnings and precautions section of labeling for the GLP-1 obesity drugs Eli Lilly and Co.s Zepbound (tirzepatide) and Novo Nordisk A/S Saxenda (liraglutide) and Wegovy (semaglutide)

Results: The XB model showed superior performance compared to both RF and Cox regression in predicting left atrial enlargement (LAE) (PR-AUC = 0.71, specificity = 75%, sensitivity = 64%), left ventricular (LV) akinesia (PR-AUC = 0.44, specificity = 96%, sensitivity = 54%), and aortic plaques (PR-AUC = 0.29, specificity = 27%, sensitivity = 79%)