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Zhang GQ

13:858676 Granata S, Votrico V, Spadaccino F, Catalano V, Netti GS, Ranieri E et al (2022) Oxidative stress and ischemia/reperfusion injury in kidney transplantation: focus on ferroptosis mitophagy and new antioxidants

LAR: Leucoanthocyanidin reductase

We show that TCA cycle activity links lipid and carbohydrate catabolism to ER homeostasis through production of NADPH and redox regulation of glutathione

Peroxynitrite is highly toxic to neurons and causes hyper-excitability of the central nervous system, a process known as "kindling." This leads to autonomic nervous system dysfunction (dysautonomia), sensory overload, and severe cognitive deficits

doi: 10.1186/1750-1172-2-16