glp-1 titration receptor agonists in the treatment of type 2 diabetes – state-of-the-art glp-1 dose titration guidelines clinical

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Unlike blurry vision caused by temporary changes in blood sugar levels or shifts in the shape of the eyes lens, NAION involves structural injury to the optic nerve itself and can result in irreversible damage

Sleep quality can be affected by both the autoimmune condition and, at higher doses, by GLP-1 therapy itself

It has therefore been postulated that gut-derived GLP-1 may not achieve sufficient concentration to stimulate distant cell GLP-1 receptors, and that an cell, rather than an enteroendocrine source of GLP-1, regulates insulin secretion under diabetic conditions (18)