Biotin, also known as vitamin B7, is popular for its benefits for hair, skin, and nails
This is most likely a result of GLP-1 receptor agonists producing the desired effect, weight loss, as opposed to a direct effect of GLP-1 receptor agonists on reduced gallbladder emptying or suppression of cholecystokinin, which has been hypothesized
More specifically, it's an incretin hormone that triggers insulin secretion only in response to food intake , as its effects are glucose-dependent and primarily activated when blood glucose levels are elevated
The GIPR is also highly expressed on pancreatic -cells, as well as on adipocytes and in the brain
This triple-action mechanism distinguishes it from existing approved therapies such as semaglutide (a GLP-1 receptor agonist) or tirzepatide (a dual GIP/GLP-1 agonist)
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