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BPC-157 demonstrates a bell-shaped dose-response curve in several models, meaning too high a dose may reduce therapeutic effects. Sikiric, P

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Further supporting the idea that the cerebellum may be responsible for tremor generation, experiments conducted with animal models of harmaline-induced tremor have shown that enhanced coupling of the inferior olivary neurons can produce rhythmic discharges of the downstream cerebellum that drive tremor [184]

[DOI] [PMC free article] [PubMed] [Google Scholar] Tanous C

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