Berberine ameliorates obesity by inducing GDF15 secretion by brown adipocytes
however, the hypothesis was that the absence of fever, rather than the presence of APAP, might be a problem
Currently, diagnosis is made via oral patient history
Peer review Peer review information Nature Communications thanks Reza Vafabakhsh, Sudarshan Rajagopal and the anonymous reviewer(s) for their contribution to the peer review of this work
doi: 10.1038/s41422-020-00441-1 20 YuYJiangLWangHShenZChengQZhangPet al
The translational pathway would benefit from early thoughts from materials science, clinical, and regulatory experts to co-design delivery formats (e.g., special nanocomposite antimicrobial coatings that rapidly kill persisters on catheters) and to co-plan staged clinical trials with microbiological markers of success (i.e., MBEC reduction and no relapse) and not just surrogates of colonization