Current clinical treatment guidelines aim for a functional cure for CHB, which involves sustained negativity for hepatitis B surface antigen (HBsAg), undetectable HBV DNA, normal liver biochemical indicators, and improvement of liver tissue lesions after treatment cessation
Clin Cancer Res 11 : 49124922 Munster P, Marchion D, Bicaku E, Schmitt M, Lee JH, DeConti R, Simon G, Fishman M, Minton S, Garrett C, Chiappori A, Lush R, Sullivan D, Daud A (2007) Phase I trial of histone deacetylase inhibition by valproic acid followed by the topoisomerase II inhibitor epirubicin in advanced solid tumors: a clinical and translational study
Excess ROS activates inflammasome pathways, including NLRP3 inflammasome, promoting pyroptosis, an inflammatory form of cell death (Fig
The results suggest that gene regulation in Alzheimers disease is more complex than previously understood
The government, responding to safety concerns, decided that Medicare would not cover any weight loss drugs, and this restriction has remained in place ever since
In: Hertz L (ed)