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An in vitro model of cerebral Ischemia-Reperfusion was established using oxygen-glucose deprivation and reoxygenation (OGD/R)

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Importantly, brain endothelial cells are known to gain their specialized BBB functions through interactions with other cells of NVU such as pericytes, astrocytes, and neurons ( The decline of BBB and BCB are involved in many neurological diseases (Zenaro et al., 2017) and Parkinsons disease (Oby and Janigro, 2006), etc

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No, because Kysse already has lidocaine, a powerful numbing agent, mixed in

It was first discovered in 1973 by Dr