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Compared to Sermorelin (truncated native GHRH 1-29, 10-15 minute half-life), Tesamorelin offers significantly superior plasma stability thanks to its DPP-IV resistance
[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations
10.1046/j.1523-1747.2002.19507.x J
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