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The LDSC analysis indicated a significant association (rg = 0.36, P = 3.40 10 46 ) between T2D and SA

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22,23 In the liver, GLP-1RAs can also decrease hepatic gluconeogenesis and enhance glucose uptake, which can improve circulating glucose levels

agents that increase GLP-1 action are used to treat type 2 diabetes mellitus GLP-2 regulates nutrient absorption by the gastrointestinal tract through enhancement of intestinal growth, nutrient digestion and transport, as well as blood flow The physiologic role of oxyntomodulin remains to be established, but exogenous administration suppresses food intake