Effective January 1, 2026, Medi-Cal Rx is excluding coverage for GLP-1 medications prescribed for weight loss: [12] Wegovy, Zepbound, Saxenda: Completely removed from the Contract Drugs List for weight loss Ozempic, Mounjaro, Rybelsus: Restricted to Type 2 diabetes onlyweight loss claims will auto-deny Existing prior authorizations end December 31, 2025 Exceptions: Members under age 21 may still qualify via EPSDT Non-weight-loss indications (Zepbound for OSA, Wegovy for cardiovascular) may still get PA approval This does NOT affect Kaiser commercial or employer-sponsored plansonly Medi-Cal members
It helps to control blood sugar levels
Same titration ladder applied to research-grade lyophilized vials, with insulin-syringe units for each step
At this time, more research is needed to understand how they work and whether they truly have anti-inflammatory properties
During this time, many also notice improvements in blood sugar control, which is especially beneficial for individuals with type 2 diabetes
Before starting or continuing both medications together, ensure you discuss: Your Complete Medical History: Previous or current mental health conditions, including depression, anxiety, bipolar disorder, or suicidal ideation History of seizures or conditions that lower seizure threshold Eating disorders (past or present) Cardiovascular disease, including hypertension Kidney or liver impairment Thyroid disorders Diabetes and current glycaemic control Gastrointestinal conditions, including pancreatitis or gallbladder disease Eligibility for Wegovy under NICE guidelines (typically requiring specialist weight management services, specific BMI thresholds, and other criteria) All Current Medications: Provide a complete list including: Prescription medications (especially anticoagulants like warfarin, antidiabetic drugs, or medications affecting seizure threshold such as tramadol, antipsychotics, tricyclic antidepressants, or quinolone antibiotics) Medications that affect CYP2B6 enzymes which metabolise bupropion Over-the-counter medicines Herbal supplements and vitamins Recreational substances or alcohol use Treatment Goals and Monitoring: Discuss realistic expectations for weight management and smoking cessation
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