The market is highly competitive, with over 60 companies developing GLP-1 drugs and more than 135 candidates in clinical trials
Ingredients worth looking for alongside berberine: Astragalus root supports cardiovascular function and may extend berberines effects on insulin sensitivity Ginger root extract anti-inflammatory, supports glucose regulation and digestive motility Cinnamon bark extract studied for blood sugar support through mechanisms distinct from berberine Artichoke leaf extract supports liver health and cholesterol metabolism Single-ingredient berberine products leave all of this unaddressed
Ethyl acetate extract components of bushen-yizhi formula provides neuroprotection against scopolamine-induced cognitive impairment
Conversely, a failure to reduce oxidative stress resulted in supplemental vitamin E being more detrimental to the cognitive function of AD patients than placebo
Glutathione levels fall with age and tend to be lower in many chronic and neurodegenerative conditions
With no berberine, no chromium, and no probiotic or gut-microbiome support, it targets a much smaller part of the GLP-1 pathway