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Since NNMT is expressed in adipose, hepatic, and gut tissues 50,51,52 , and these tissues heavily cross-talk with the gut microbiome 53,54,55 , NNMTi treatment or its resulting weight loss effects 8,9 may modulate the microbiome
It is important to know your B12 levels and response to treatment so that your healthcare provider can determine the appropriate dosing schedule
MOTS-c activates AMPK pathways to improve insulin sensitivity, mitochondrial function, and metabolic flexibility
Its suggested to give this dose daily or every other day for one to two weeks to effectively address the deficiency
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