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Ann Vasc surg (2021) 73:25463
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(2002) Enzymatic oxidation products of spermine induce greater cytotoxic effects on human multidrug-resistant colon carcinoma cells (LoVo) than on their wild-type counterparts Int J Cancer
Brain cells also consume oxygen at high rates, leading to a proportionally high mitochondrial production of reactive species
In addition, the reviewer gathered English-language studies on antioxidant supplements therapeutic controversies during cancer treatment, primarily from North and South America, Europe, and Asia, without considering cultural and socioeconomic disparities, requiring caution in application
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