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As such, we observed a reduction in DNA damage, measured by H2AX staining using flow cytometry, in 1919 cells with amplification of PSPH and PSPH V116I , both at baseline and in response to a 4 Gy irradiation (Figure S11)

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Anti-Inflammatory Properties: Reduces scalp inflammation and lowers cytokines that contribute to follicle damage and miniaturization

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Moreover, androgen synthesis is upregulated by IGF2 that increases the expression of steroidogenic enzymes including steroid acute regulatory protein, cytochrome p450 family member 17A1, aldo-keto reductase family member 1C3, and hydroxysteroid dehydrogenase 17B3 [111, 112]

Sep 2021;14(3):208-217