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How GLP-1 Weight Loss Works GLP-1 (glucagon-like peptide-1) is a hormone your body naturally produces when you eat

doi:10.1016/j.molmet.2020.101102 Graaf C, Donnelly D, Wootten D, et al

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Serious adverse effects such as severe abdominal pain (which may indicate pancreatitis), persistent vomiting leading to dehydration, or signs of thyroid tumors (neck mass, difficulty swallowing, persistent hoarseness) require immediate medical attention

Although leuprolide is not approved for this indication in Canada, some physicians may choose to use leuprolide in conjunction with mecasermin, particularly among patients who are near an adult height or for whom bone age is rapidly increasing