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Furthermore, the complexities of the biological functions of DPP-4 are indeed multiplying with diverse bioactive substrates of DPP-4, thus emphasizing the elegant role of DPP-4 in the biochemical tuning of multiple cell type and tissues

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For individuals with arthritis, achieving and maintaining weight loss can be challenging due to: Pain-related activity limitation , making exercise difficult Reduced mobility affecting ability to engage in physical activity Medication side effects , as some arthritis treatments may affect metabolism Nevertheless, structured weight management programmes combining dietary modification, physical activity tailored to individual capabilities, and behavioural support have proven effective

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