However, under oxidative stress, cysteine residues on KEAP1 are modified, altering its conformation and disrupting its association with NRF2 and subsequent NRF2 stabilization (Taguchi and Yamamoto, 2017)
So its best to go over this with your doctor for a personalized fit that also addresses any comorbidities or concurrent meds
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Hyperandrogenism People with PCOS also experience elevated levels of androgens (male hormones), and this leads to: Hirsutism (excess hair growth) : Increased body and facial hair growth
Increased production of ROS and RNS usually result in production of more potent peroxynitrite (ONOO ), which interacts with cellular macromolecules such as DNA, proteins, and lipids to produce oxidized DNA, proteins, and lipid peroxides, respectively [46]
So part of clearing brain fog is literally refueling your nervous system