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Sleep gets shallower

Prospective studies should incorporate clinically meaningful endpoints rather than surrogate mechanistic outcomes

Budimirovic, D

Dosage and Route: Sublingual tablets are dissolved under the tongue roughly 2-3 hours prior to bedtime, on an empty stomach, depending on individual patient response

Activated microglia acquire either an M1 phenotype and release pro-inflammatory cytokines, or an M2 phenotype associated with the release of anti-inflammatory cytokines [2]

Ensure laterality (right, left, unspecified) is properly documented