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For many experts, the FLOW results represented an important turning point

Many people face similar challenges, finding it difficult to achieve and maintain their weight loss goals

The quantity of sleep is known to be associated (in a U shaped manner) with health outcomes (e.g

GLP-1RAs and CVOTs Available GLP-1RAs (except for exenatide twice daily) have been examined in multicentre, double-blinded, randomised, placebo-controlled cardiovascular (CV) outcomes trials (CVOTs)

176 GLP-1RAs and diseases As a rising star in recent years, GLP-1RAs are not only effective in metabolic diseases but also play a role in non-metabolic disorders, affecting multiple systems including the musculoskeletal, nervous, cardiovascular, and digestive systems, and can even have implications in oncological diseases

However, given the safety or effectiveness concerns of anti-obesity drugs, many of the currently used drugs have limited clinical use