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The process typically involves a consultation with a healthcare provider and blood tests to confirm a deficiency

In the anabolic methionine cycle, niacin, in the form of NAD, is a necessary co-factor for the enzymes dihydrofolate reductase in the folate/tetrahydrobiopterin cycle and S-adenosylhomocysteine hydrolase (1)

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10.1016/S1097-2765(04)00256-4 62

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