For analytical testing, this means: RP-HPLC and LC-MS/MS methods developed and validated against Novo Nordisks recombinant semaglutide reference standards may not fully characterize impurities in synthetically produced samples, and vice versa
Similarly models were developed using dipeptide and tripeptide composition resulted in R/R 2 of 0.68/0.46 and 0.69/0.47 with MAE 1.44 and 1.38 respectively (Table 1)
This blog is part of an ongoing series on A Brave New World: Therapeutic Area Deep Dives
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