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Once your levels are normal, you may need 100-500 micrograms a day or 1,000 micrograms one or two times a week

If side effects occur, they are usually mild and temporary

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For the targeted analysis 8 fmol of Cytochrome C digest was added to the samples before injection in LC-MS/MS (Thermo Scientific)

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Overall, more studies in pediatric patients are needed, including those with a larger sample size conducted in individuals managed according to current guidelines