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Standard community protocols run tirzepatide alone for the first 8 weeks (2.5 5 mg/week) to confirm GI tolerance, then add cagrilintide at 0.25 mg/week starting Week 9

These users report appreciating treatment benefits while active but watching improvements gradually fade over months post-discontinuation, with timeline showing first 2 months maintaining most benefits creating initial optimism, months 2-4 showing noticeable decline returning toward baseline, months 4-8 continuing regression approaching pre-treatment status, and stabilization occurring 60-80% back toward original baseline with only modest long-term improvement retention

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At IM FABULOUS COSMETICS, formulation is everything

For the standard skincare anchor, add 2.5 mL of BAC water