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Current clinical evidence does not support combining these substances safely, and most healthcare providers advise against it

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This guide is for patients using or considering GLP-1 medications for weight loss, including semaglutide or tirzepatide, who want to understand which side effects are common and which symptoms should lead to a call with a physician

No data gaps

Based on the role of PKCs, and PRKCG in particular, it is critical to revisit the potential use of drugs that modulate PKC activity to explore psychiatric treatments, given PKCs role in memory and learning via LTP, and its wide-ranging span of biological activity in the CNS

Sukhorukov 1,2 1 Russian enter of Neurology and Neurosciences, 80 Volokolamskoe Shosse, Moscow 125367 Russia 2 Pirogov Russian National Research Medical University, 1 Ostrovityanova Str., Moscow 117997 Russia Corresponding author: Dmitry N