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This conversion primarily happens in the liver with the help of 5-deiodinase enzymes

4.1 Medication routes and obstacles for the treatment of eye diseases The anterior segment of the eye is composed of the cornea, conjunctiva, iris, ciliary body, crystalline lens, and aqueous humor, while the posterior segment of the eye includes the posterior two-thirds of the eye, including the vitreous, retina, choroid, and optic nerve (Vaneev et al., 2021)

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When activated, these cells undergo morphological changes that enable them to increase and perform phagocytosis