The review included a comprehensive search of peer-reviewed articles published between January 2010 and November 2024 conducted using the PubMed and Medline databases, supplemented by the inclusion of relevant studies from earlier periods when clinically justified
The obesity issue in the U.S
Integration of scRNA-seq with epigenomic approaches, such as single-cell sequencing assay for transposase-accessible chromatin (scATAC-seq) and DNA methylation profiling, allows identification of regulatory elements governing the expression of key genes, including those involved in survival, proliferation, and insulin secretion (Leenders et al., 2024
Effect of ertugliflozin on glucose control, body weight, blood pressure and bone density in type 2 diabetes mellitus inadequately controlled on metformin monotherapy (VERTIS MET)
In: Narayanan, A.S., Dharumadurai, D
However, Phase 2 trials are not always powered or designed to detect rare psychiatric adverse events, and longer-term Phase 3 data which would provide a more comprehensive safety profile had not been fully published at the time of writing