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As obesity increasingly contributes to musculoskeletal disability, therapies addressing both weight and inflammation may become more central to osteoarthritis care

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GLP-1 receptor agonists (GLP-1RAs) are a relatively novel class of antidiabetic drugs that have gained popularity in recent years due to a number of associated benefits, such as a very low risk of hypoglycaemia, concomitant weight loss and cardiovascular benefits [4, 5]