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(%) Weighted incidence rate per 1000 person-years a Main analysis 124 517 77 (0.06) 0.23 174 036 71 (0.04) 0.18 1.25 (0.83 to 1.88) 0.05 (0.03 to 0.16) Analyses by country Sweden 77 495 60 (0.08) 0.28 108 881 46 (0.04) 0.19 1.44 (0.87 to 2.37) 0.08 (0.02 to 0.26) Denmark 47 022 17 (0.04) 0.15 65 155 25 (0.04) 0.16 0.94 (0.46 to 1.91) 0.01 (0.09 to 0.15) Subgroup analyses History of psychiatric disorder 52 090 58 (0.11) 0.43 62 843 51 (0.08) 0.33 1.25 (0.77 to 2.02) 0.08 (0.08 to 0.34) No history of psychiatric disorder 72 420 18 (0.02) 0.09 111 083 20 (0.02) 0.07 1.44 (0.71 to 2.92) 0.03 (0.02 to 0.13) Initiating liraglutide 62725 53 (0.08) 0.23 65 875 40 (0.06) 0.16 1.35 (0.85 to 2.15) 0.06 (0.02 to 0.19) Initiating semaglutide 49 478 8 (0.02) 0.14 49 176 13 (0.03) 0.19 0.74 (0.33 to 1.67) 0.05 (0.13 to 0.13) Additional analyses As-treated exposure definition 124 517 41 (0.03) 0.19 174 036 37 (0.02) 0.15 1.27 (0.76 to 2.15) 0.04 (0.04 to 0.17) Analysis restricted to first y of follow-up 124 517 18 (0.01) 0.17 174 036 23 (0.01) 0.15 1.11 (0.54 to 2.28) 0.02 (0.07 to 0.20) a Standardized mortality ratio weighting using a propensity score

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