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The repurposing of already approved GLP-1RAs for the treatment of NDD may be a safe, efficient, and cost-effective strategy for improving the patients condition by suppressing neuroinflammation [46]
cohort study, the 2-year discontinuation rate for GLP-1 receptor agonists was 64.1% among people with type 2 diabetes mellitus, driven by factors such as older age, low income, gastrointestinal adverse events, and insufficient weight loss [115]
J Diabetes Sci Technol
-Among patients with type 2 diabetes, semaglutide use was associated with significantly lower odds of NAION (OR 0.36, 95% CI 0.250.51) compared with nonGLP-1 therapies
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Comparative effectiveness of glucagon-like peptide-1 receptor agonists, sodium-glucose cotransporter 2 inhibitors, dipeptidyl peptidase-4 inhibitors, and sulfonylureas for sight-threatening diabetic retinopathy
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