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Structurally, tesamorelin is GHRH(144) modified with a trans-3-hexenoic acid group that extends its plasma half-life from minutes to approximately 3038 minutes more stable than native GHRH, but still requiring daily subcutaneous injection

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The abdomen (avoiding a 2-inch radius around the navel), outer thigh, and upper arm provide suitable injection locations with adequate subcutaneous tissue

10.1155/2022/4026688 75 ZhangL.YuefangL.MinH.WenboC.DuanL.LiuZ.et al (2022b)

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