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Originally developed to manage diabetes, these medications began showing significant weight reduction in clinical trials
A., Yates, T., Khunti, K., & Davies, M
Their seemingly miraculous properties have been praised by tech CEOs, podcaster Joe Rogan, and celebrities such as Gwyneth Paltrow, Jennifer Aniston, and Kim Kardashian, who says her daily regimen "changed my life." But many doctors are alarmed by a craze that has thousands of people injecting themselves with substances of dubious origin and whose long-term effects are unknown
Supplements can interact with prescription medications and may not be appropriate for people with certain medical conditions
Because MPTP is a lipophilic compound, it can cross the BBB, and be taken up by astrocytes where it is converted to MPP+
doi: 10.1016/j.beem.2009.03.001
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