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(February 2012)

10.2147/dddt.s361972 44 FarkhondehT.FolgadoS

A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation

[55] This specificity reflects the distinct metabolic roles of the respective coenzymes, and is the result of distinct sets of amino acid residues in the two types of coenzyme-binding pocket

With multiple studies considering HO as a feasible target, the treatment of DN seems to have new prospects