It downregulated ACSL4 and CD71 expression, significantly increased the expression of System Xc , GPX4, and Ferritin, reduced ROS levels, and inhibited ferroptosis, inflammatory responses, and mitochondrial dysfunction in BV2 cells
10.1016/j.arr.2021.101536 25 PaiV
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Studies show senescent fibroblasts in diabetic wounds exhibit resistance to ferroptosis, a potential driver of their pathological accumulation
Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel JC, Decker H, et al
But what you eat while your appetite is suppressed matters enormously for body composition, energy levels, and long-term outcomes