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General cell culture and imaging The HeLa cell line used in this study was purchased from American Type Culture Collection (ATCC) and grown in DMEM (Gibco, 11965) media supplemented with 10% FBS and 1% 1003 Pen Strep (Gibco)

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Where feasible, authors should align ROS and oxidative damage assays with consensus best-practice guidance ( 6.5 Design rules and reporting considerations Rigorous silicaphenolic development benefits from a minimal evidence stack that connects materials identity to redox biology and translation

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Other actions of melatonin such as SEEM consist of the inhibition of the desmoplastic reaction due to the ability to promote the expression of transcription factors (PPAR and c/EBP) involved in the differentiation of fibroblasts into mature adipocytes