Put simply, semaglutide works by stimulating GLP-1 (glucagon-like peptide-1) receptors, which are responsible for appetite and food intake regulation
By mimicking its effects, semaglutide helps control hunger, slow digestion, and improve insulin sensitivity, allowing the body to burn fat and regulate blood sugar levels more effectively
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With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success. The study, Optimal Timing for Cessation of GLP-1 Agonist Before Elective Total Hip and Knee Arthroplasty, obtained data from the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA from January 1, 2018 to January 1, 2023
The tablet must be taken alone on an empty stomach, and other oral medicines should wait at least 30 minutes